Therapeutic effects of Anacardium occidentale: an integrative review
Abstract
Anacardium occidentale is characterized as a medicinal plant, member of the Anacardiaceae family. Different parts of the plant have multiple pharmaceutical properties, which are related to their derivatives and high levels of secondary metabolites. Thus, the aim of the study is to identify evidence available in the literature about the herbal properties of A. occidentale in articles published in the last ten years. This is an integrative literature review using descriptors in the Virtual Health Library (VHL) used in the PubMed and SciELO databases. In such a way, the research resulted in 603 articles and, after employing the inclusion and exclusion criteria, totaled 51 publications for the full analysis. 97 different properties of A. occidentale were found: anti-inflammatory; antioxidant; antimicrobial; antidiabetic; healing; analgesic; effects on the digestive tract; in the autonomic nervous, respiratory and blood system; hypotensive and cardio inhibitory effects; protective against male sexual dysfunction; antimutagenic, antimetastatic and clastogenic; odontological use; toxic and non-toxic effect and others. The antimicrobial effect was the main one to be reported, however, its applicability in phytotherapy is diverse, having a significant capacity to act in pharmacological treatments if there is adequate contribution to research and development of new drugs.
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References
Adriano-Anaya, L., Trejo-Roblero, G., Rosas-Quijano, R., Velázquez-Ovalle, G., & Vázquez-Ovando, A. (2017). Mejoramiento del rendimiento y calidad del fruto y pseudofruto de marañonL. con un ciclo de fertilización orgánica. Revista Brasileira de Fruticultura, 39(5), 674. doi: 10.1590/0100-29452017674
Aguilar, Y. M., Rodríguez, F. S., Saavedra, M. A., C., Espinosa, R. H., & Yero, O. M. (2012). Secondary metabolites and in vitro antibacterial activity of extracts from Anacardium occidentale L. (Cashew tree) leaves. Revista Cubana de Plantas Medicinales, 17(4), 320-329.
Aguilar, Y. M., Yero, O. M., Arias, A. E., Rodríguez, F. S., & Navarro, M. V. (2012). Composición química y tamizaje fitoquímico del polvo de hojas y retoños del Anacardium occidentale L. (marañón). Revista Cubana de Plantas Medicinales, 17(1), 1-10. Recovered from http://scielo.sld.cu/scielo.php?pid=S1028-47962012000100001&script=sci_arttext&tlng=pt
Aguilar, Y. M., Yero, O. M., Olmos, E. S., Siza, S. I., & Betancur, C. H. (2012). Efecto nutracéutico del Anacardium occidentale en dietas de pollitas ponedoras de reemplazo. Revista MVZ Cordoba, 17(3), 3125-3132. doi: 10.21897/rmvz.211
Akpan, E. E., & Ekrikpo, U. E. (2015). Acute Renal Failure Induced by Chinese Herbal Medication in Nigeria. Case Reports in Medicine, 2015. doi: 10.1155/2015/150204
Albertasse, P. D., Thomaz, L. D., & Andrade, M. A. (2010). Plantas medicinais e seus usos na comunidade da Barra do Jucu, Vila Velha, ES. Revista Brasileira de Plantas Medicinais, 12(3), 250-260. doi: 10.1590/s1516-05722010000300002
Almeida, M. O., Bezerra, T. T., Lima, N. M. A., Sousa, A. F., Trevisan, M. T. S., Ribeiro, V. G. P., Lomonaco, D., & Mazzetto, S. E. (2019). Cardol-Derived Organophosphorothioates as Inhibitors of Acetylcholinesterase for Dengue Vector Control. Journal of the Brazilian Chemical Society, 30(12), 2634-2641. doi: 10.21577/0103-5053.20190181
Anand, G., Ravinanthan, M., Basaviah, R., & Shetty, A. (2015). In vitro antimicrobial and cytotoxic effects of Anacardium occidentale and Mangifera indica in oral care. Journal of Pharmacy and Bioallied Sciences, 7(1), 69-74. doi: 10.4103/0975-7406.148780
Baptista, A., Gonçalves, R. V., Bressan, J., & do Carmo Gouveia Pelúzio, M. (2018). Antioxidant and antimicrobial activities of crude extracts and fractions of cashew (Anacardium occidentale L.), cajui (Anacardium microcarpum), and pequi (Caryocar brasiliense C.): A systematic review. Oxidative Medicine and Cellular Longevity, 2018. doi: 10.1155/2018/3753562
Matutino Bastos, T., Mannochio Russo, H., Silvio Moretti, N., Schenkman, S., Marcourt, L., Gupta, M., … Botelho Pereira Soares, M. (2019). Chemical Constituents of Anacardium occidentale as Inhibitors of Trypanosoma cruzi Sirtuins. Molecules, 24(7), 1299-1312. doi: 10.3390/molecules24071299
Botelho, L. L. R., Cunha, C. C. de A., & Macedo, M. (2011). O Método Da Revisão Integrativa Nos Estudos Organizacionais. Gestão e Sociedade, 5(11), 121-136. doi: 10.21171/ges.v5i11.1220
Brasil. (2016). Política Nacional e Programa Nacional de Plantas Medicinais e Fitoterápicos. Ministério da Saúde. Available on: http://bvsms.saude.gov.br/bvs/publicacoes/politica_programa_nacional_plantas_medicinais_fitoterapicos.pdf
Carrenho, P. R. B., Silva, A. C., Uebel, J. R., & Agostini, J. S. (2019). Physical-chemical characterization, microbiological and biocompounds of cashew pulp in industrial and freezing processing. Food Science and Technology, 2019(1), 1-7. doi: 10.1590/fst.01419
Chaves, E. M. F., & Barros, R. F. M. (2012). Diversidade e uso de recursos medicinais do carrasco na APA da Serra da Ibiapaba, Piauí, Nordeste do Brasil. Revista Brasileira de Plantas Medicinais, 14(3), 476-486. doi: 10.1590/S1516- 05722012000300009
Chaves, M. H., Citó, A. M. das G. L., Lopes, J. A. D., da Costa, D. A., de Oliveira, C. A. A., Francisco, A. F. C., & Brito Júnior, E. M. (2010). Fenóis totais, atividade antioxidante e constituintes químicos de extratos de Anacardium occidentale L., Anacardiaceae. Brazilian Journal of Pharmacognosy, 20(1), 106-112. doi: 10.1590/s0102-695x2010000100021
Chikezie, P. C. (2011). Sodium metabisulfite-induced polymerization of sickle cell hemoglobin incubated in the extracts of three medicinal plants (Anacardium occidentale, Psidium guajava, and Terminalia catappa). Pharmacognosy Magazine, 7(26), 126-132. doi: 10.4103/0973-1296.80670
Chikezie, P. C., & Uwakwe, A. A. (2011). Membrane stability of sickle erythrocytes incubated in extracts of three medicinal plants: Anacardium occidentale, Psidium guajava, and Terminalia catappa. Pharmacognosy Magazine, 7(26), 121-125. doi: 10.4103/0973-1296.80669
Chotphruethipong, L., Benjakul, S., & Kijroongrojana, K. (2019). Ultrasound Assisted Extraction of Antioxidative Phenolics From Cashew (Anacardium occidentale L.) Leaves. Journal of Food Science and Technology, 56(1), 1785-1792. doi: 10.1007/s13197-019-03617-9
Chung, S., Shin, E. J., Choi, H. K., Park, J. H., & Hwang, J. T. (2020). Anacardic Acid Mitigates Liver Fat Accumulation and Impaired Glucose Tolerance in Mice Fed a High-Fat and High-Sucrose Diet. Food Science & Nutrition, 8(2), 796-804. doi: 10.1002/fsn3.1322
Costa A. C. P. J. et al., (2020). Effects of Cashew Nut (Anacardium occidentale L.) Seed Flour in Moderately Malnourished Children: Randomized Clinical Trial. Journal of the Nutrition and Metabolism, 2020(1). doi: 10.1155/2020/6980754
Dias C. C. Q., Madruga M. S., Pintado M. M. E., Almeida G. H. O., Alves A. P. V., Dantas F. A,…Soares J, K. B. (2019). Cashew Nuts (Anacardium Occidentale L.) Decrease Visceral Fat, Yet Augment Glucose in Dyslipidemic Rats. Plos One, 14(12). doi: 10.1371/journal.pone.0225736
Duangjan C., Rangsinth P., Gu X., Wink, M., & Tencomnao T. (2019). Lifespan Extending and Oxidative Stress Resistance Properties of a Leaf Extracts From Anacardium occidentale L. In Caenorhabditis elegans. Oxidative Medicine and Cellular Longevity, 2019(1). doi: 10.1155/2019/9012396
Fusco, R., Siracusa, R., Peritore, A. F., Gugliandolo, E., Genovese, T., D’Amico, R., & Di Paola, R. (2020). The Role of Cashew (Anacardium occidentale L.) Nuts on an Experimental Model of Painful Degenerative Joint Disease. Antioxidants (Basel), 9(6). doi: 10.3390/antiox9060511
Gimenez, V., Alvarenga, T., Groppo, M., Silva, M., Cunha, W., Januário, A., Smilkstein, M., Riscoe, M., & Pauletti, P., (2019). Antiplasmodial evaluation of Anacardium occidentale and alkyl-phenols. Revista Brasileira de Farmacognosia, 29(1), 36-39. doi: 10.1016/j.bjp.2018.11.003
Gomes, C. E. B., Cavalcante, D. G., Filho, J. E. G., Da Costa, F. N., & Da Silva Pereira, S. L. (2016). Clinical effect of a mouthwash containing Anacardium occidentale Linn. on plaque and gingivitis control: A rand/omized controlled trial. Indian Journal of Dental Research, 27(4), 364-369. doi; 10.4103/0970-9290.191883
Gonçalves, G. M. S., & Gobbo, J. (2012). Antimicrobial effect of Anacardium occidentale extract and cosmetic formulation development. Brazilian Archives of Biology and Technology, 55(6), 843-850. doi: 10.1590/S1516- 89132012000600006
Hemshekhar, M., Sebastin Santhosh, M., Kemparaju, K., & Girish, K. S. (2012). Emerging roles of anacardic acid and its derivatives: A pharmacological overview. Basic and Clinical Pharmacology and Toxicology, 110(2), 122-132. doi: 10.1111/j.1742-7843.2011.00833.x
Jaiswal, Y. S., Tatke, P. A., Gabhe, S. Y., & Vaidya, A. B. (2017). Antidiabetic activity of extracts of Anacardium occidentale Linn. leaves on n-streptozotocin diabetic rats. Journal of Traditional and Complementary Medicine, 7(4), 421-427. https://doi.org/10.1016/j.jtcme.2016.11.007
Khan, I. N., Razibul Habib, M., Mominur Rahman, M., Mannan, A., Mominul Islam Sarker, M., & Hawlader, S. (2011). Thrombolytic potential of Ocimum sanctum L., Curcuma longa L., Azadirachta indica L. and Anacardium occidentale L. Journal of Basic and Clinical Pharmacy, 002(003), 125-127. Recovered from www.jbclinpharm.com
Lima, A. C. S., Soares, D. J., Da Silva, L. M. R., De Figueiredo, R. W., De Sousa, P. H. M., & De Abreu Menezes, E. (2014). In vitro bioaccessibility of copper, iron, zinc and antioxidant compounds of whole cashew apple juice and cashew apple fibre (Anacardium occidentale L.) following simulated gastro-intestinal digestion. Food Chemistry, 161, 142-147. doi: 10.1016/j.foodchem.2014.03.123
Lopes, M. M. de A., Miranda, M. R. A. de, Moura, C. F. H., & Enéas Filho, J. (2012). Bioactive compounds and total antioxidant capacity of cashew apples (Anacardium occidentale L.) during the ripening of early dwarf cashew clones. Ciência e Agrotecnologia, 36(3), 325-332. doi: 10.1590/s1413-70542012000300008
Mendes, A., Dionísio, A., Mouta, C., Abreu, F., Pinto, C., Garruti, D., & Araújo, I., (2019). Sensory acceptance and characterization of yoghurt supplemented with yacon syrup and cashew apple extract as a source of bioactive compounds. Brazilian Journal of Food Technology, 22(1). doi: 10.1590/1981-6723.15318
Miranda, J., Barreto, J., Martins, D., Souza Pimentel, P., Silva Costa, D., Silva, R.,…Cerqueira, G., (2019). Protective Effect of Cashew Gum (Anacardium Occidentale L.) on 5-Fluorouracil-Induced Intestinal Mucositis. Pharmaceuticals (Basel), 12(5), 1-9. doi: 10.3390/ph12020051
Montanari, R. M., Barbosa, L. C. A., Demuner, A. J., Silva, C. J., Andrade, N. J., Ismail, F. M. D., & Barbosa, M. C. A. (2012). Exposure to anacardiaceae volatile oils and their constituents induces lipid peroxidation within food-borne bacteria cells. Molecules, 17(8), 9728-9740. doi: 10.3390/molecules17089728
Morais, S. M., Silva, K. A., Araujo, H., Vieira, I. G. P., Alves, D. R., Fontenelle, R. O. S., & Silva, A. M. S. (2017). Anacardic acid constituents from cashew nut shell liquid: NMR characterization and the effect of unsaturation on its biological activities. Pharmaceuticals, 10(1), 1-10. doi: 10.3390/ph10010031
Moyses-Neto, M., Brito, B. R. S., De Araújo Brito, D. J., Barros, N. D. C., Dantas, M., Salgado-Filho, N., & Silva, G. E. B. (2018). Vitamin C-induced oxalate nephropathy in a renal transplant patient related to excessive ingestion of cashew pseudofruit (Anacardium occidentale L.): A case report 11 Medical and Health Sciences 1103 Clinical Sciences. BMC Nephrology, 19(1), 1-4. doi: 10.1186/s12882-018-1060-9
Mujica, V., Delgado, M., Ramírez, M., Pérez, C., Rodríguez-Corella, M., & Velásquez, I. (2010). Formulation of a cosmetic product with anti-wrinkle properties based on cashew seed oil (Anacardium Occidentale L). Revista de La Facultad de Ingenieria, 25(2), 119-131.
Neiva, V. do A., Ribeiro, M. N. S., Nascimento, F. R. F., Cartágenes, M. do S. S., Coutinho-Moraes, D. F., & do Amaral, F. M. M. (2014). Plant species used in giardiasis treatment: Ethnopharmacology and in vitro evaluation of anti-Giardia activity. Brazilian Journal of Pharmacognosy, 24(2), 215-224. doi: 10.1016/j.bjp.2014.04.004
Okonkwo, T. J. N., Okorie, O., Okonta, J. M., & Okonkwo, C. J. (2010). Sub-chronic hepatotoxicity of Anacardium occidentale (Anacardiaceae) inner stem bark extract in rats. Indian Journal of Pharmaceutical Sciences, 72(3), 353-357. doi: 10.4103/0250-474X.70482
Okpashi, V. E., Bayim, B. P. R., & Obi-Abang, M. (2014). Comparative effects of some medicinal plants: Anacardium occidentale, Eucalyptus globulus, Psidium guajava, and Xylopia aethiopica extracts in alloxan-induced diabetic male wistar albino rats. Biochemistry Research International, 2014. doi: 10.1155/2014/203051
Owumi, S. E., Fatoki, J. O., Gbadegesin, M. A., & Odunola, O. A. (2015). Clastogenic and toxicological assessment of cashew (Anacardium occidentale) nut bark extracts in Wistar rats. Acta Biochimica Polonica, 62(3), 563-567. doi: 10.18388/abp.2015_1024
Oyedemi, S. O., Oyedemi, B. O., Ijeh, I. I., Ohanyerem, P. E., Coopoosamy, R. M., & Aiyegoro, O. A. (2017). Alpha-Amylase Inhibition and Antioxidative Capacity of Some Antidiabetic Plants Used by the Traditional Healers in Southeastern Nigeria. Scientific World Journal, 2017. doi: 10.1155/2017/3592491
Quelemes, P. V., Araruna, F. B., Faria, B. E. F., Kuckelhaus, S. A. S., Silva, D. A., Mendonça, R. Z., & Leite, J. R. S. A. (2013). Development and antibacterial activity of cashew gum-based silver nanoparticles. International Journal of Molecular Sciences, 14(3), 4969-4981. doi: 10.3390/ijms14034969
Rabelo, M. C., Brito, E. S., Moura, C. F. H., Oliveira, L. D. S., & De Miranda, M. R. A. (2016). Estabilidade térmica de enzimas antioxidantes e deteriorantes dos sucos de graviola e caju. Revista Brasileira de Fruticultura, 38(2), 338. doi: 10.1590/0100-29452016338
Rico, R., Bulló, M., & Salas-Salvadó, J. (2015). Nutritional composition of raw fresh cashew (Anacardium occidentale L.) kernels from different origin. Food Science and Nutrition, 4(2), 329-338. doi: 10.1002/fsn3.294
Romero Dominguez, M. J., Bravo Henríquez, A. R., Sintjago Maury, E. A., & Esteva Ferrer, E. K. (2012). Efectos del consumo de una bebida de cajuil (Anacardium occidentale) sobre la respuesta glucémica e insulínica en pacientes con diabetes mellitus tipo 2. Perspectivas En Nutrición Humana, 14(1), 11-21. Recovered from http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0124-41082012000100002&lng=en
Roumy, V., Gutierrez-Choquevilca, A.-L., Lopez Mesia, J., Ruiz, L., Ruiz Macedo, J., Abedini, A., & Neut, C. (2015). In vitro antimicrobial activity of traditional plant used in mestizo shamanism from the Peruvian amazon in case of infectious diseases. Pharmacognosy Magazine, 11(44), 625. doi: 10.4103/0973-1296.172975
Salehi, Gültekin-Özgüven, Kırkın, Özçelik, Morais-Braga, Carneiro, Bezerra, Silva, Coutinho, Amina, Armstrong, Selamoglu, Sevindik, Yousaf, Sharifi-Rad, Muddathir, Devkota, Martorell, Jugran, Martins and Cho, (2019). Anacardium Plants: Chemical,Nutritional Composition and Biotechnological Applications. Biomolecules, 9(9), 465-498. doi: 10.3390/biom9090465
Santos, A. B. N., Araújo, M. P., Sousa, R. S., & Lemos, J. R. (2016). Plantas medicinais conhecidas na zona urbana de Cajueiro da Praia, Piauí, Nordeste do Brasil. Revista Brasileira de Plantas Medicinais, 18(2), 442-450. https://doi.org/10.1590/1983-084X/15_149
Santos, E. B., Dantas, G. S., Santos, H. B., Melo Diniz, M. F. F., & Sampaio, F. C. (2009). Estudo etnobotânico de plantas medicinais para problemas bucais no município de João Pessoa, Brasil. Brazilian Journal of Pharmacognosy, 19(1B), 321-324. doi: 10.1590/S0102-695X2009000200024
Santos, G. H. F., Silva, E. B., Silva, B. L., Sena, K. X. F. R., & Lima, C. S. A. (2011). Influence of gamma radiation on the antimicrobial activity of crude extracts of Anacardium occidentale rich in tannins. Brazilian Journal of Pharmacognosy, 21(3), 444-449. doi: 10.1590/S0102-695X2011005000045
Shilpa, P., Kaveri, K., & Salimath, B. P. (2015). Anti-metastatic action of anacardic acid targets VEGF-induced signalling pathways in epithelial to mesenchymal transition. Drug Discoveries & Therapeutics, 9(1), 53-65. doi: 10.5582/ddt.2014.01042
Silva, D. P. B., Florentino, I. F., da Silva Moreira, L. K., Brito, A. F., Carvalho, V. V., Rodrigues, M. F., & Costa, E. A. (2018). Chemical characterization and pharmacological assessment of polysaccharide free, standardized cashew gum extract (Anacardium occidentale L.). Journal of Ethnopharmacology, 213(October 2017), 395-402. doi: 10.1016/j.jep.2017.11.021
Silva, M. I. G., Melo, C. T. V. De, Vasconcelos, L. F., Carvalho, A. M. R. De, & Sousa, F. C. F. (2012). Bioactivity and potential therapeutic benefits of some medicinal plants from the Caatinga (semi-arid) vegetation of Northeast Brazil: a review of the literature. Revista Brasileira de Farmacognosia, 22(1), 193-207. doi: 10.1590/S0102-695X2011005000171
Singh, R. (2009). Antihyperglycemic effect of ethanolic extract and fractions of Anacardium occidentale L. Stem bark in streptozotocin-induced diabetic rats. Journal of Basic and Clinical Pharmacy, 1(1), 16-169.
Silveira Vasconcelos, M., Gomes-Rochette, N. F., de Oliveira, M. L. M., Nunes- Pinheiro, D.C. S., Tomé, A. R., Maia de Sousa, F. Y., & de Melo, D. F. (2015). Anti- inflammatory and wound healing potential of cashew apple juice (Anacardium occidentale L.) in mice. Experimental Biology and Medicine, 240(12), 1648-1655. doi: 10.1177/1535370215576299
Siracusa, R., Fusco, R., Peritore, A., Cordaro, M., D’Amico, R., Genovese, T., Gugliandolo, E., Crupi, R., Smeriglio, A., Mandalari, G., Cuzzocrea, S., Di Paola, R. and Impellizzeri, D., (2020). The Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale L. Cashew Nuts in a Mouse Model of Colitis. Nutrients, 12(3), 834-854. doi: 10.3390/nu12030834
Souza, C. M. P., Brandão, D. O., Silva, M. S. P., Palmeira, A. C., Simões, M. O. S., & Medeiros, A. C. D. (2013). Utilização de Plantas Medicinais com Atividade Antimicrobiana por Usuários do Serviço Público de Saúde em Campina Grande - Paraíba. Revista Brasileira de Plantas Medicinais, 15(2), 188-193. doi: 10.1590/S1516-05722013000200004
Souza, M. Q., Teotônio, I. M. S. N., de Almeida, F. C., Heyn, G. S., Alves, P. S., Romeiro, L. A. S., & Pratesi, C. B. (2018). Molecular evaluation of anti-inflammatory activity of phenolic lipid extracted from cashew nut shell liquid (CNSL). BMC Complementary and Alternative Medicine, 18(1), 1-11. doi: 10.1186/s12906-018-2247-0
Souza, N. C., Oliveira, J. M., Da Silva Morrone, M., Albanus, R. D. O., Amarante, M. D. S. M., Da Silva Camillo, C., & De Bittencourt Pasquali, M. A. (2017). Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale Leaf Extract. Evidence-Based Complementary and Alternative Medicine, 2017. doi: 10.1155/2017/2787308
Sunderam, V., Thiyagarajan, D., Lawrence, A., Mohammed, S., & Selvaraj, A., (2019). In-vitro Antimicrobial and Anticancer Properties of Green Synthesized Gold Nanoparticles Using Anacardium occidentale Leaves Extract. Saudi Journal of Biological Sciences, 26(3), 455-459. doi: 10.1016/j.sjbs.2018.12.001
Stasiuk, M., Janiszewska, A., & Kozubek, A. (2014). Phenolic lipids affect the activityand conformation of acetylcholinesterase from Electrophorus electricus (Electric eel). Nutrients, 6(5), 1823-1831. doi: 10.3390/nu6051823
Tchikaya, F. O., Bantsielé, G. B., Kouakou-Siransy, G., Datté, J. Y., Yapo, P. A., Zirihi, N. G., & Offoumou, M. A. (2011). Anacardium occidentale Linn. (Anacardiaceae) stem bark extract induces hypotensive and cardio-inhibitory effects in experimental animal models. African Journal of Traditional, Complementary and Alternative Medicines, 8(4), 452-461. doi: 10.4314/ajtcam.v8i4.18
Vanderlinde, F. A., Landim, H. F., Costa, E. A., Galdino, P. M., Maciel, M. A. M., Dos Anjos, G. C., & Da Rocha, F. F. (2009). Evaluation of the antinociceptive and anti-inflammatory effects of the acetone extract from Anacardium occidentale L. Brazilian Journal of Pharmaceutical Sciences, 45(3), 437-442. doi: 10.1590/S1984-82502009000300008
Vieira, D. R. P., Amaral, F. M. M., Maciel, M. C. G., Nascimento Flávia, F. R. F., & Libério, A. S. (2014). Plantas e constituintes químicos empregados em Odontologia: Revisão de estudos etnofarmacológicos e de avaliação da atividade antimicrobiana in vitro em patógenos orais. Revista Brasileira de Plantas Medicinais, 16(1), 135-167. doi: 10.1590/S1516-05722014000100020
Vieira, L. M., Sousa, M. S. B., Mancini-Filho, J., & de Lima, A. (2011). Fenólicos totais e capacidade antioxidante in vitro de polpas de frutos tropicais. Revista Brasileira de Fruticultura, 33(3), 888-897. doi: 10.1590/S0100-29452011005000099
Vilar, M. S., Souza, G. L., Araújo Vilar, D., Leite, J. A., Raffin, F. N., Barbosa-Filho, J. M., & Lima Moura, T. F. A. (2016). Assessment of phenolic compounds and anti-inflammatory activity of ethyl acetate phase of Anacardium occidentale L. bark. Molecules, 21(8). doi: 10.3390/molecules21081087
Wattanathorn, J., Prabsattroo, T., Somsapt, P., Sritragool, O., Thukham-Mee, W., & Muchimapura, S. (2018). Sexual Enhancing Effect of Anacardium occidentale in Stress-Exposed Rats by Improving Dopaminergic and Testicular Functions. BioMed Research International, 2018. doi: 10.1155/2018/6452965
World Health Organization. (2003). Guidelines on good agricultural and collection practices (GACP) for medicinal plants. World Health Organization.
Aguilar, Y. M., Rodríguez, F. S., Saavedra, M. A., C., Espinosa, R. H., & Yero, O. M. (2012). Secondary metabolites and in vitro antibacterial activity of extracts from Anacardium occidentale L. (Cashew tree) leaves. Revista Cubana de Plantas Medicinales, 17(4), 320-329.
Aguilar, Y. M., Yero, O. M., Arias, A. E., Rodríguez, F. S., & Navarro, M. V. (2012). Composición química y tamizaje fitoquímico del polvo de hojas y retoños del Anacardium occidentale L. (marañón). Revista Cubana de Plantas Medicinales, 17(1), 1-10. Recovered from http://scielo.sld.cu/scielo.php?pid=S1028-47962012000100001&script=sci_arttext&tlng=pt
Aguilar, Y. M., Yero, O. M., Olmos, E. S., Siza, S. I., & Betancur, C. H. (2012). Efecto nutracéutico del Anacardium occidentale en dietas de pollitas ponedoras de reemplazo. Revista MVZ Cordoba, 17(3), 3125-3132. doi: 10.21897/rmvz.211
Akpan, E. E., & Ekrikpo, U. E. (2015). Acute Renal Failure Induced by Chinese Herbal Medication in Nigeria. Case Reports in Medicine, 2015. doi: 10.1155/2015/150204
Albertasse, P. D., Thomaz, L. D., & Andrade, M. A. (2010). Plantas medicinais e seus usos na comunidade da Barra do Jucu, Vila Velha, ES. Revista Brasileira de Plantas Medicinais, 12(3), 250-260. doi: 10.1590/s1516-05722010000300002
Almeida, M. O., Bezerra, T. T., Lima, N. M. A., Sousa, A. F., Trevisan, M. T. S., Ribeiro, V. G. P., Lomonaco, D., & Mazzetto, S. E. (2019). Cardol-Derived Organophosphorothioates as Inhibitors of Acetylcholinesterase for Dengue Vector Control. Journal of the Brazilian Chemical Society, 30(12), 2634-2641. doi: 10.21577/0103-5053.20190181
Anand, G., Ravinanthan, M., Basaviah, R., & Shetty, A. (2015). In vitro antimicrobial and cytotoxic effects of Anacardium occidentale and Mangifera indica in oral care. Journal of Pharmacy and Bioallied Sciences, 7(1), 69-74. doi: 10.4103/0975-7406.148780
Baptista, A., Gonçalves, R. V., Bressan, J., & do Carmo Gouveia Pelúzio, M. (2018). Antioxidant and antimicrobial activities of crude extracts and fractions of cashew (Anacardium occidentale L.), cajui (Anacardium microcarpum), and pequi (Caryocar brasiliense C.): A systematic review. Oxidative Medicine and Cellular Longevity, 2018. doi: 10.1155/2018/3753562
Matutino Bastos, T., Mannochio Russo, H., Silvio Moretti, N., Schenkman, S., Marcourt, L., Gupta, M., … Botelho Pereira Soares, M. (2019). Chemical Constituents of Anacardium occidentale as Inhibitors of Trypanosoma cruzi Sirtuins. Molecules, 24(7), 1299-1312. doi: 10.3390/molecules24071299
Botelho, L. L. R., Cunha, C. C. de A., & Macedo, M. (2011). O Método Da Revisão Integrativa Nos Estudos Organizacionais. Gestão e Sociedade, 5(11), 121-136. doi: 10.21171/ges.v5i11.1220
Brasil. (2016). Política Nacional e Programa Nacional de Plantas Medicinais e Fitoterápicos. Ministério da Saúde. Available on: http://bvsms.saude.gov.br/bvs/publicacoes/politica_programa_nacional_plantas_medicinais_fitoterapicos.pdf
Carrenho, P. R. B., Silva, A. C., Uebel, J. R., & Agostini, J. S. (2019). Physical-chemical characterization, microbiological and biocompounds of cashew pulp in industrial and freezing processing. Food Science and Technology, 2019(1), 1-7. doi: 10.1590/fst.01419
Chaves, E. M. F., & Barros, R. F. M. (2012). Diversidade e uso de recursos medicinais do carrasco na APA da Serra da Ibiapaba, Piauí, Nordeste do Brasil. Revista Brasileira de Plantas Medicinais, 14(3), 476-486. doi: 10.1590/S1516- 05722012000300009
Chaves, M. H., Citó, A. M. das G. L., Lopes, J. A. D., da Costa, D. A., de Oliveira, C. A. A., Francisco, A. F. C., & Brito Júnior, E. M. (2010). Fenóis totais, atividade antioxidante e constituintes químicos de extratos de Anacardium occidentale L., Anacardiaceae. Brazilian Journal of Pharmacognosy, 20(1), 106-112. doi: 10.1590/s0102-695x2010000100021
Chikezie, P. C. (2011). Sodium metabisulfite-induced polymerization of sickle cell hemoglobin incubated in the extracts of three medicinal plants (Anacardium occidentale, Psidium guajava, and Terminalia catappa). Pharmacognosy Magazine, 7(26), 126-132. doi: 10.4103/0973-1296.80670
Chikezie, P. C., & Uwakwe, A. A. (2011). Membrane stability of sickle erythrocytes incubated in extracts of three medicinal plants: Anacardium occidentale, Psidium guajava, and Terminalia catappa. Pharmacognosy Magazine, 7(26), 121-125. doi: 10.4103/0973-1296.80669
Chotphruethipong, L., Benjakul, S., & Kijroongrojana, K. (2019). Ultrasound Assisted Extraction of Antioxidative Phenolics From Cashew (Anacardium occidentale L.) Leaves. Journal of Food Science and Technology, 56(1), 1785-1792. doi: 10.1007/s13197-019-03617-9
Chung, S., Shin, E. J., Choi, H. K., Park, J. H., & Hwang, J. T. (2020). Anacardic Acid Mitigates Liver Fat Accumulation and Impaired Glucose Tolerance in Mice Fed a High-Fat and High-Sucrose Diet. Food Science & Nutrition, 8(2), 796-804. doi: 10.1002/fsn3.1322
Costa A. C. P. J. et al., (2020). Effects of Cashew Nut (Anacardium occidentale L.) Seed Flour in Moderately Malnourished Children: Randomized Clinical Trial. Journal of the Nutrition and Metabolism, 2020(1). doi: 10.1155/2020/6980754
Dias C. C. Q., Madruga M. S., Pintado M. M. E., Almeida G. H. O., Alves A. P. V., Dantas F. A,…Soares J, K. B. (2019). Cashew Nuts (Anacardium Occidentale L.) Decrease Visceral Fat, Yet Augment Glucose in Dyslipidemic Rats. Plos One, 14(12). doi: 10.1371/journal.pone.0225736
Duangjan C., Rangsinth P., Gu X., Wink, M., & Tencomnao T. (2019). Lifespan Extending and Oxidative Stress Resistance Properties of a Leaf Extracts From Anacardium occidentale L. In Caenorhabditis elegans. Oxidative Medicine and Cellular Longevity, 2019(1). doi: 10.1155/2019/9012396
Fusco, R., Siracusa, R., Peritore, A. F., Gugliandolo, E., Genovese, T., D’Amico, R., & Di Paola, R. (2020). The Role of Cashew (Anacardium occidentale L.) Nuts on an Experimental Model of Painful Degenerative Joint Disease. Antioxidants (Basel), 9(6). doi: 10.3390/antiox9060511
Gimenez, V., Alvarenga, T., Groppo, M., Silva, M., Cunha, W., Januário, A., Smilkstein, M., Riscoe, M., & Pauletti, P., (2019). Antiplasmodial evaluation of Anacardium occidentale and alkyl-phenols. Revista Brasileira de Farmacognosia, 29(1), 36-39. doi: 10.1016/j.bjp.2018.11.003
Gomes, C. E. B., Cavalcante, D. G., Filho, J. E. G., Da Costa, F. N., & Da Silva Pereira, S. L. (2016). Clinical effect of a mouthwash containing Anacardium occidentale Linn. on plaque and gingivitis control: A rand/omized controlled trial. Indian Journal of Dental Research, 27(4), 364-369. doi; 10.4103/0970-9290.191883
Gonçalves, G. M. S., & Gobbo, J. (2012). Antimicrobial effect of Anacardium occidentale extract and cosmetic formulation development. Brazilian Archives of Biology and Technology, 55(6), 843-850. doi: 10.1590/S1516- 89132012000600006
Hemshekhar, M., Sebastin Santhosh, M., Kemparaju, K., & Girish, K. S. (2012). Emerging roles of anacardic acid and its derivatives: A pharmacological overview. Basic and Clinical Pharmacology and Toxicology, 110(2), 122-132. doi: 10.1111/j.1742-7843.2011.00833.x
Jaiswal, Y. S., Tatke, P. A., Gabhe, S. Y., & Vaidya, A. B. (2017). Antidiabetic activity of extracts of Anacardium occidentale Linn. leaves on n-streptozotocin diabetic rats. Journal of Traditional and Complementary Medicine, 7(4), 421-427. https://doi.org/10.1016/j.jtcme.2016.11.007
Khan, I. N., Razibul Habib, M., Mominur Rahman, M., Mannan, A., Mominul Islam Sarker, M., & Hawlader, S. (2011). Thrombolytic potential of Ocimum sanctum L., Curcuma longa L., Azadirachta indica L. and Anacardium occidentale L. Journal of Basic and Clinical Pharmacy, 002(003), 125-127. Recovered from www.jbclinpharm.com
Lima, A. C. S., Soares, D. J., Da Silva, L. M. R., De Figueiredo, R. W., De Sousa, P. H. M., & De Abreu Menezes, E. (2014). In vitro bioaccessibility of copper, iron, zinc and antioxidant compounds of whole cashew apple juice and cashew apple fibre (Anacardium occidentale L.) following simulated gastro-intestinal digestion. Food Chemistry, 161, 142-147. doi: 10.1016/j.foodchem.2014.03.123
Lopes, M. M. de A., Miranda, M. R. A. de, Moura, C. F. H., & Enéas Filho, J. (2012). Bioactive compounds and total antioxidant capacity of cashew apples (Anacardium occidentale L.) during the ripening of early dwarf cashew clones. Ciência e Agrotecnologia, 36(3), 325-332. doi: 10.1590/s1413-70542012000300008
Mendes, A., Dionísio, A., Mouta, C., Abreu, F., Pinto, C., Garruti, D., & Araújo, I., (2019). Sensory acceptance and characterization of yoghurt supplemented with yacon syrup and cashew apple extract as a source of bioactive compounds. Brazilian Journal of Food Technology, 22(1). doi: 10.1590/1981-6723.15318
Miranda, J., Barreto, J., Martins, D., Souza Pimentel, P., Silva Costa, D., Silva, R.,…Cerqueira, G., (2019). Protective Effect of Cashew Gum (Anacardium Occidentale L.) on 5-Fluorouracil-Induced Intestinal Mucositis. Pharmaceuticals (Basel), 12(5), 1-9. doi: 10.3390/ph12020051
Montanari, R. M., Barbosa, L. C. A., Demuner, A. J., Silva, C. J., Andrade, N. J., Ismail, F. M. D., & Barbosa, M. C. A. (2012). Exposure to anacardiaceae volatile oils and their constituents induces lipid peroxidation within food-borne bacteria cells. Molecules, 17(8), 9728-9740. doi: 10.3390/molecules17089728
Morais, S. M., Silva, K. A., Araujo, H., Vieira, I. G. P., Alves, D. R., Fontenelle, R. O. S., & Silva, A. M. S. (2017). Anacardic acid constituents from cashew nut shell liquid: NMR characterization and the effect of unsaturation on its biological activities. Pharmaceuticals, 10(1), 1-10. doi: 10.3390/ph10010031
Moyses-Neto, M., Brito, B. R. S., De Araújo Brito, D. J., Barros, N. D. C., Dantas, M., Salgado-Filho, N., & Silva, G. E. B. (2018). Vitamin C-induced oxalate nephropathy in a renal transplant patient related to excessive ingestion of cashew pseudofruit (Anacardium occidentale L.): A case report 11 Medical and Health Sciences 1103 Clinical Sciences. BMC Nephrology, 19(1), 1-4. doi: 10.1186/s12882-018-1060-9
Mujica, V., Delgado, M., Ramírez, M., Pérez, C., Rodríguez-Corella, M., & Velásquez, I. (2010). Formulation of a cosmetic product with anti-wrinkle properties based on cashew seed oil (Anacardium Occidentale L). Revista de La Facultad de Ingenieria, 25(2), 119-131.
Neiva, V. do A., Ribeiro, M. N. S., Nascimento, F. R. F., Cartágenes, M. do S. S., Coutinho-Moraes, D. F., & do Amaral, F. M. M. (2014). Plant species used in giardiasis treatment: Ethnopharmacology and in vitro evaluation of anti-Giardia activity. Brazilian Journal of Pharmacognosy, 24(2), 215-224. doi: 10.1016/j.bjp.2014.04.004
Okonkwo, T. J. N., Okorie, O., Okonta, J. M., & Okonkwo, C. J. (2010). Sub-chronic hepatotoxicity of Anacardium occidentale (Anacardiaceae) inner stem bark extract in rats. Indian Journal of Pharmaceutical Sciences, 72(3), 353-357. doi: 10.4103/0250-474X.70482
Okpashi, V. E., Bayim, B. P. R., & Obi-Abang, M. (2014). Comparative effects of some medicinal plants: Anacardium occidentale, Eucalyptus globulus, Psidium guajava, and Xylopia aethiopica extracts in alloxan-induced diabetic male wistar albino rats. Biochemistry Research International, 2014. doi: 10.1155/2014/203051
Owumi, S. E., Fatoki, J. O., Gbadegesin, M. A., & Odunola, O. A. (2015). Clastogenic and toxicological assessment of cashew (Anacardium occidentale) nut bark extracts in Wistar rats. Acta Biochimica Polonica, 62(3), 563-567. doi: 10.18388/abp.2015_1024
Oyedemi, S. O., Oyedemi, B. O., Ijeh, I. I., Ohanyerem, P. E., Coopoosamy, R. M., & Aiyegoro, O. A. (2017). Alpha-Amylase Inhibition and Antioxidative Capacity of Some Antidiabetic Plants Used by the Traditional Healers in Southeastern Nigeria. Scientific World Journal, 2017. doi: 10.1155/2017/3592491
Quelemes, P. V., Araruna, F. B., Faria, B. E. F., Kuckelhaus, S. A. S., Silva, D. A., Mendonça, R. Z., & Leite, J. R. S. A. (2013). Development and antibacterial activity of cashew gum-based silver nanoparticles. International Journal of Molecular Sciences, 14(3), 4969-4981. doi: 10.3390/ijms14034969
Rabelo, M. C., Brito, E. S., Moura, C. F. H., Oliveira, L. D. S., & De Miranda, M. R. A. (2016). Estabilidade térmica de enzimas antioxidantes e deteriorantes dos sucos de graviola e caju. Revista Brasileira de Fruticultura, 38(2), 338. doi: 10.1590/0100-29452016338
Rico, R., Bulló, M., & Salas-Salvadó, J. (2015). Nutritional composition of raw fresh cashew (Anacardium occidentale L.) kernels from different origin. Food Science and Nutrition, 4(2), 329-338. doi: 10.1002/fsn3.294
Romero Dominguez, M. J., Bravo Henríquez, A. R., Sintjago Maury, E. A., & Esteva Ferrer, E. K. (2012). Efectos del consumo de una bebida de cajuil (Anacardium occidentale) sobre la respuesta glucémica e insulínica en pacientes con diabetes mellitus tipo 2. Perspectivas En Nutrición Humana, 14(1), 11-21. Recovered from http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0124-41082012000100002&lng=en
Roumy, V., Gutierrez-Choquevilca, A.-L., Lopez Mesia, J., Ruiz, L., Ruiz Macedo, J., Abedini, A., & Neut, C. (2015). In vitro antimicrobial activity of traditional plant used in mestizo shamanism from the Peruvian amazon in case of infectious diseases. Pharmacognosy Magazine, 11(44), 625. doi: 10.4103/0973-1296.172975
Salehi, Gültekin-Özgüven, Kırkın, Özçelik, Morais-Braga, Carneiro, Bezerra, Silva, Coutinho, Amina, Armstrong, Selamoglu, Sevindik, Yousaf, Sharifi-Rad, Muddathir, Devkota, Martorell, Jugran, Martins and Cho, (2019). Anacardium Plants: Chemical,Nutritional Composition and Biotechnological Applications. Biomolecules, 9(9), 465-498. doi: 10.3390/biom9090465
Santos, A. B. N., Araújo, M. P., Sousa, R. S., & Lemos, J. R. (2016). Plantas medicinais conhecidas na zona urbana de Cajueiro da Praia, Piauí, Nordeste do Brasil. Revista Brasileira de Plantas Medicinais, 18(2), 442-450. https://doi.org/10.1590/1983-084X/15_149
Santos, E. B., Dantas, G. S., Santos, H. B., Melo Diniz, M. F. F., & Sampaio, F. C. (2009). Estudo etnobotânico de plantas medicinais para problemas bucais no município de João Pessoa, Brasil. Brazilian Journal of Pharmacognosy, 19(1B), 321-324. doi: 10.1590/S0102-695X2009000200024
Santos, G. H. F., Silva, E. B., Silva, B. L., Sena, K. X. F. R., & Lima, C. S. A. (2011). Influence of gamma radiation on the antimicrobial activity of crude extracts of Anacardium occidentale rich in tannins. Brazilian Journal of Pharmacognosy, 21(3), 444-449. doi: 10.1590/S0102-695X2011005000045
Shilpa, P., Kaveri, K., & Salimath, B. P. (2015). Anti-metastatic action of anacardic acid targets VEGF-induced signalling pathways in epithelial to mesenchymal transition. Drug Discoveries & Therapeutics, 9(1), 53-65. doi: 10.5582/ddt.2014.01042
Silva, D. P. B., Florentino, I. F., da Silva Moreira, L. K., Brito, A. F., Carvalho, V. V., Rodrigues, M. F., & Costa, E. A. (2018). Chemical characterization and pharmacological assessment of polysaccharide free, standardized cashew gum extract (Anacardium occidentale L.). Journal of Ethnopharmacology, 213(October 2017), 395-402. doi: 10.1016/j.jep.2017.11.021
Silva, M. I. G., Melo, C. T. V. De, Vasconcelos, L. F., Carvalho, A. M. R. De, & Sousa, F. C. F. (2012). Bioactivity and potential therapeutic benefits of some medicinal plants from the Caatinga (semi-arid) vegetation of Northeast Brazil: a review of the literature. Revista Brasileira de Farmacognosia, 22(1), 193-207. doi: 10.1590/S0102-695X2011005000171
Singh, R. (2009). Antihyperglycemic effect of ethanolic extract and fractions of Anacardium occidentale L. Stem bark in streptozotocin-induced diabetic rats. Journal of Basic and Clinical Pharmacy, 1(1), 16-169.
Silveira Vasconcelos, M., Gomes-Rochette, N. F., de Oliveira, M. L. M., Nunes- Pinheiro, D.C. S., Tomé, A. R., Maia de Sousa, F. Y., & de Melo, D. F. (2015). Anti- inflammatory and wound healing potential of cashew apple juice (Anacardium occidentale L.) in mice. Experimental Biology and Medicine, 240(12), 1648-1655. doi: 10.1177/1535370215576299
Siracusa, R., Fusco, R., Peritore, A., Cordaro, M., D’Amico, R., Genovese, T., Gugliandolo, E., Crupi, R., Smeriglio, A., Mandalari, G., Cuzzocrea, S., Di Paola, R. and Impellizzeri, D., (2020). The Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale L. Cashew Nuts in a Mouse Model of Colitis. Nutrients, 12(3), 834-854. doi: 10.3390/nu12030834
Souza, C. M. P., Brandão, D. O., Silva, M. S. P., Palmeira, A. C., Simões, M. O. S., & Medeiros, A. C. D. (2013). Utilização de Plantas Medicinais com Atividade Antimicrobiana por Usuários do Serviço Público de Saúde em Campina Grande - Paraíba. Revista Brasileira de Plantas Medicinais, 15(2), 188-193. doi: 10.1590/S1516-05722013000200004
Souza, M. Q., Teotônio, I. M. S. N., de Almeida, F. C., Heyn, G. S., Alves, P. S., Romeiro, L. A. S., & Pratesi, C. B. (2018). Molecular evaluation of anti-inflammatory activity of phenolic lipid extracted from cashew nut shell liquid (CNSL). BMC Complementary and Alternative Medicine, 18(1), 1-11. doi: 10.1186/s12906-018-2247-0
Souza, N. C., Oliveira, J. M., Da Silva Morrone, M., Albanus, R. D. O., Amarante, M. D. S. M., Da Silva Camillo, C., & De Bittencourt Pasquali, M. A. (2017). Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale Leaf Extract. Evidence-Based Complementary and Alternative Medicine, 2017. doi: 10.1155/2017/2787308
Sunderam, V., Thiyagarajan, D., Lawrence, A., Mohammed, S., & Selvaraj, A., (2019). In-vitro Antimicrobial and Anticancer Properties of Green Synthesized Gold Nanoparticles Using Anacardium occidentale Leaves Extract. Saudi Journal of Biological Sciences, 26(3), 455-459. doi: 10.1016/j.sjbs.2018.12.001
Stasiuk, M., Janiszewska, A., & Kozubek, A. (2014). Phenolic lipids affect the activityand conformation of acetylcholinesterase from Electrophorus electricus (Electric eel). Nutrients, 6(5), 1823-1831. doi: 10.3390/nu6051823
Tchikaya, F. O., Bantsielé, G. B., Kouakou-Siransy, G., Datté, J. Y., Yapo, P. A., Zirihi, N. G., & Offoumou, M. A. (2011). Anacardium occidentale Linn. (Anacardiaceae) stem bark extract induces hypotensive and cardio-inhibitory effects in experimental animal models. African Journal of Traditional, Complementary and Alternative Medicines, 8(4), 452-461. doi: 10.4314/ajtcam.v8i4.18
Vanderlinde, F. A., Landim, H. F., Costa, E. A., Galdino, P. M., Maciel, M. A. M., Dos Anjos, G. C., & Da Rocha, F. F. (2009). Evaluation of the antinociceptive and anti-inflammatory effects of the acetone extract from Anacardium occidentale L. Brazilian Journal of Pharmaceutical Sciences, 45(3), 437-442. doi: 10.1590/S1984-82502009000300008
Vieira, D. R. P., Amaral, F. M. M., Maciel, M. C. G., Nascimento Flávia, F. R. F., & Libério, A. S. (2014). Plantas e constituintes químicos empregados em Odontologia: Revisão de estudos etnofarmacológicos e de avaliação da atividade antimicrobiana in vitro em patógenos orais. Revista Brasileira de Plantas Medicinais, 16(1), 135-167. doi: 10.1590/S1516-05722014000100020
Vieira, L. M., Sousa, M. S. B., Mancini-Filho, J., & de Lima, A. (2011). Fenólicos totais e capacidade antioxidante in vitro de polpas de frutos tropicais. Revista Brasileira de Fruticultura, 33(3), 888-897. doi: 10.1590/S0100-29452011005000099
Vilar, M. S., Souza, G. L., Araújo Vilar, D., Leite, J. A., Raffin, F. N., Barbosa-Filho, J. M., & Lima Moura, T. F. A. (2016). Assessment of phenolic compounds and anti-inflammatory activity of ethyl acetate phase of Anacardium occidentale L. bark. Molecules, 21(8). doi: 10.3390/molecules21081087
Wattanathorn, J., Prabsattroo, T., Somsapt, P., Sritragool, O., Thukham-Mee, W., & Muchimapura, S. (2018). Sexual Enhancing Effect of Anacardium occidentale in Stress-Exposed Rats by Improving Dopaminergic and Testicular Functions. BioMed Research International, 2018. doi: 10.1155/2018/6452965
World Health Organization. (2003). Guidelines on good agricultural and collection practices (GACP) for medicinal plants. World Health Organization.
Published
2020-09-28
How to Cite
PADILHA, Janine Agra et al.
Therapeutic effects of Anacardium occidentale: an integrative review.
Acta Brasiliensis, [S.l.], v. 4, n. 3, p. 178-186, sep. 2020.
ISSN 2526-4338.
Available at: <http://revistas.ufcg.edu.br/actabra/index.php/actabra/article/view/368>. Date accessed: 12 nov. 2024.
doi: https://doi.org/10.22571/2526-4338368.
Section
Review
